Blastocyst Grading
Blastocyst Grading
การให้เกรดตัวอ่อนระยะบลาสโตซิส
การให้เกรดตัวอ่อนระยะบลาสโตซิส
Dr. Patsama Vichinsartvichai,
MClinEmbryol, EFOG-EBCOG, EFRM-EBCOG.
Dr. Patsama Vichinsartvichai,
MClinEmbryol, EFOG-EBCOG, EFRM-EBCOG.
Embryology Timeline
3 Cleavage,
8 cells
0
1; 2PN
5, 6 Blastocyst
Day
The Blastocyst
Inner Cell Mass
(ICM)
Trophectoderm
(TE)
Zona Pellucida
Blastocoel
Perivitelline Space
Blastocyst Grading
4
B
A
4
Expansion Status
1
Very early blastocyst
2
Early blastocyst
3
Full blastocyst
4
Expanded blastocyst
5
Hatching
blastocyst
6
Hatched
blastocyst
B
A
Tightly packed, many cells;
Quality of ICM
B
Loosely grouped, several cells
C
Very few cells.
A
Quality of TE
A
B
C
Many cells forming a cohesive epithelium;
Few cells forming a loose epithelium
Very few cells.
Example
4
A
B
Example
3
C
C
References
- Gardner DK, Lane M, Stevens J, Schoolcraft WB. Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer. Fertil Steril. 2000;73(6):1155–1158.
- Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology, The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting, Human Reproduction, Volume 26, Issue 6, 1 June 2011, Pages 1270–1283,